Psychedelics After Stroke: What Is Actually Known

This is the question in our name, and it is the question we get asked most.

Here is the whole of it, including the parts that are disappointing.

The Short Version

In the research we have reviewed, we have not identified human evidence that psilocybin, DMT, Ketamine, or another psychedelic improves stroke recovery or a stroke outcome.

What does exist: human trial evidence in other conditions, especially depression. Animal studies exploring psychedelics in experimental stroke. And a Phase 1 study at Johns Hopkins evaluating the safety of psilocybin in chronic stroke survivors.

There is real reason to take the question seriously.

There is no reason yet to believe the answer.